Endocrine Abstracts

The effectiveness of glucocorticoid replacement therapy is based on clinical criteria, since objectives parameters are not standardized. The purpose of our study was to assess the adequacy of replacement therapy with cortisone acetate, trying to identify parameters indicating proper replacement. We studied 22 patients with adrenal insufficiency (7 primary and 15 secondary) treated with cortisone acetate (mean daily dose 36.5+/−2.1 mg at 0800 a.m. and 0300 p.m.), and six ...